The museum's permanent exhibit recounts Sisteron's history, highlighting the impact the natural environment has had on the evolution of the site, situated at the glacial threshhold of the Val de Durance, a crucial passageway between the Alps and the Mediterranean. The museum's archeological collections and visual documents cover the period spanning from prehistory to modern times and present the specificities of this highly strategic territory : the first traces of human occupation (prehistoric tools); indigenous creations and commerce (bronze bracelets, coins); Gallo-Roman funerary architecture (remnants of a mausoleum discovered in Sisteron); architectural ornaments (12th and 13th centuries), documents, statuary, ceramics (modern and contemporary epoch).